Vladinol f, neolignan compound from the stem bark of dryobalanops oblongifolia (Dipterocarpaceae) and antiplasmodial activity

Indriani, N. S. Aminah, N. N.Tri Puspaningsih, I. H. Hasna, Y. Takaya, P. Satrimafitrah

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Abstract

Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL.

Original languageEnglish
Pages (from-to)161-165
Number of pages5
JournalRasayan Journal of Chemistry
Volume14
Issue number1
DOIs
Publication statusPublished - 1 Jan 2021

Keywords

  • Antiplasmodial Activity
  • Drybalanops oblongifolia
  • Neolignan
  • Plasmodium falciparum
  • Vladinol F

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