Abstract
Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL.
Original language | English |
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Pages (from-to) | 161-165 |
Number of pages | 5 |
Journal | Rasayan Journal of Chemistry |
Volume | 14 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2021 |
Keywords
- Antiplasmodial Activity
- Drybalanops oblongifolia
- Neolignan
- Plasmodium falciparum
- Vladinol F