Update on the challenges of treating burning mouth syndrome

Michelle Suhartono, Natasha Winona Audrey, Tata Prasantat Mawantari, Auryn Thania Song Hadinata, Chininta Oktora Amani, Satutya Wicaksono, Prisca Agustina, Hilmy Irsyadi Hanif, Viola Stevy Setiyana, Rizkia Putri Anggraeni, Saka Winias

Research output: Contribution to journalArticlepeer-review


Burning Mouth Syndrome (BMS), an idiopathic oral disease and also neuropathy of trigeminal nerves appear in oral cavity with the burning sensation in tongue. Other presentation of BMS as its synonyms sore mouth, sore tongue, oral dysesthesia and scalding of mouth. This chronic debilitating oral condition has an obscure aetiology and pathogenesis, causing an abroad way to treat this disease. The medication for BMS must concern its local or systemic condition, which focusing on the relief of symptoms so the clinicians may able to improving the patients quality of life. The literature contains the summary of type drugs and supplements. Although effective therapies have been conducted in many concrete cases, a treatment modality offering efficacy in most cases of BMS, yet remains to be established. It is important to achieve an intensive knowledge to the physiopathological mechanism of BMS, and to compare and establish for developing drugs to improve the efficacy and safety profiles in the treatment of BMS.

Original languageEnglish
Pages (from-to)2943-2950
Number of pages8
JournalBiochemical and Cellular Archives
Publication statusPublished - 2020


  • Burning mouth syndrome
  • Clonazepam
  • Orofacial pain
  • Vitamin B complex


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