Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Mulyadi Tanjung, Tjitjik Srie Tjahjandarie, Shola Mardhiyyah, Ghinsha Zakatina Rahman, Muhammad Fajar Aldin, Ratih Dewi Saputri, Norizan Ahmat

Research output: Contribution to journalArticlepeer-review


Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM.

Original languageEnglish
Pages (from-to)58-61
Number of pages4
JournalNatural Product Sciences
Issue number2
Publication statusPublished - 2022


  • Flemingia lineata
  • cytotoxicity
  • flavanone
  • flemilineatins A-B


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