Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Mulyadi Tanjung; Tjitjik Srie Tjahjandarie; Shola Mardhiyyah; Ghinsha Zakatina Rahman; Muhammad Fajar Aldin; Ratih Dewi Saputri; Norizan Ahmat

doi:10.20307/nps.2022.28.2.58

Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Mulyadi Tanjung, Tjitjik Srie Tjahjandarie, Shola Mardhiyyah, Ghinsha Zakatina Rahman, Muhammad Fajar Aldin, Ratih Dewi Saputri, Norizan Ahmat

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC₅₀ value of 11.2 µM.

Original language	English
Pages (from-to)	58-61
Number of pages	4
Journal	Natural Product Sciences
Volume	28
Issue number	2
DOIs	https://doi.org/10.20307/nps.2022.28.2.58
Publication status	Published - 2022

Keywords

Flemingia lineata
cytotoxicity
flavanone
flemilineatins A-B

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.20307/nps.2022.28.2.58

Cite this

@article{0f2c130a0a8d44ff99588085e7ec6473,

title = "Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton",

abstract = "Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM.",

keywords = "Flemingia lineata, cytotoxicity, flavanone, flemilineatins A-B",

author = "Mulyadi Tanjung and Tjahjandarie, {Tjitjik Srie} and Shola Mardhiyyah and Rahman, {Ghinsha Zakatina} and Aldin, {Muhammad Fajar} and Saputri, {Ratih Dewi} and Norizan Ahmat",

year = "2022",

doi = "10.20307/nps.2022.28.2.58",

language = "English",

volume = "28",

pages = "58--61",

journal = "Natural Product Sciences",

issn = "1226-3907",

publisher = "Korean Society of Pharmacognosy",

number = "2",

}

TY - JOUR

T1 - Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

AU - Tanjung, Mulyadi

AU - Tjahjandarie, Tjitjik Srie

AU - Mardhiyyah, Shola

AU - Rahman, Ghinsha Zakatina

AU - Aldin, Muhammad Fajar

AU - Saputri, Ratih Dewi

AU - Ahmat, Norizan

PY - 2022

Y1 - 2022

N2 - Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM.

AB - Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM.

KW - Flemingia lineata

KW - cytotoxicity

KW - flavanone

KW - flemilineatins A-B

UR - http://www.scopus.com/inward/record.url?scp=85133869299&partnerID=8YFLogxK

U2 - 10.20307/nps.2022.28.2.58

DO - 10.20307/nps.2022.28.2.58

M3 - Article

AN - SCOPUS:85133869299

SN - 1226-3907

VL - 28

SP - 58

EP - 61

JO - Natural Product Sciences

JF - Natural Product Sciences

IS - 2

ER -

Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this