Casimiroa edulis Llave et Lex (Rutacae), popularly known as white sapote. The main aim of this study is to isolate and investigate the bioassay of the stem bark of Casimiroa edulis. Two flavonoids were isolated from the methanolic fraction of the stem bark of Casimiroa edulis. The isolated compounds can be identified as 6,7-dimethoxyflavone (1) and 5,6,2′-trimethoxyflavone (2) by using advance spectroscopic methods, including FT-IR, UV, 1D NMR, 2D NMR. Compounds 1 and 2 were evaluated for their antidiabetic and antioxidant activities. The result revealed that the two compounds did not have antidiabetic activity and antioxidant activity. This is the first phytochemical study of 6,7-dimethoxyflavone from the genus Casimiroa.
|Journal||IOP Conference Series: Earth and Environmental Science|
|Publication status||Published - 9 Jan 2019|
|Event||2nd International Conference on Collaboration Seminar of Chemistry and Industry, CoSCI 2018, in conjunction with 23rd Indonesian Society for Biochemistry and Molecular Biology, ISBMB 2018 - Surabaya, Indonesia|
Duration: 11 Oct 2018 → 12 Oct 2018