Thyrotoxic heart failure: A narrative review of pathophysiology and principle management

Yoga Alfian Noor, Eka Prasetya Budi Mulia, Jongky Hendro Prajitno

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Heart failure is one of the most common causes of morbidity and mortality worldwide. Several studies showed that hyperthyroidism is a potentially reversible cause of heart failure and should be excluded in every heart failure patient, especially in the absence of a common cause of heart failure and structural heart disease. The diagnosis approach of thyrotoxic heart failure still remains a lack of specific guidelines. It is necessary to establish a thyroid dysfunction evidence accompanied by a structural and functional heart abnormality. Several studies have shown that cardiac dysfunction and heart failure, which related to hyperthyroidism, will be resolved in less than six months after a patient has reached euthyroid state. This narrative review summarizes the literature on the pathophysiology and principle management of thyrotoxic heart failure.

Original languageEnglish
Pages (from-to)276-282
Number of pages7
JournalMalaysian Journal of Medicine and Health Sciences
Issue number2
Publication statusPublished - Apr 2021


  • Heart failure
  • Hyperthyroidism
  • Thyrotoxicosis


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