Therapy pattern of bronchodilators in chronic obstructive pulmonary disease (COPD) patients with acute exacerbations

Samirah Samirah, Toetik Aryani, Arina Dery Puspitasari, Marisa Anggia Ibrahim, Bunga Izzatul Lutfiyah, Alfian Nur Rasyid

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Acute exacerbation of chronic obstructive pulmonary disease (COPD) is a worsening condition of acute respiratory symptoms caused by microbial infection, increased air pollution, and fatigue. Objective: This study determines the pattern of bronchodilators in patients with acute exacerbations of COPD. Method: This study was observational, using the health medical records of patients with COPD at the Universitas Airlangga Hospital, Surabaya. It was conducted between January-December 2019 on male patients who received bronchodilator therapy until discharge and were from age 40 and older. Result: A total of 48 patients met the inclusion criteria. The most commonly used bronchodilator therapy for inpatients was the combination of ipratropium bromide/salbutamol sulfate 0.5 mg/2.5 mg through inhalation in 63.64%. The most frequently used bronchodilator for discharge was salbutamol sulfate 2-4 mg orally in 87.50%. Conclusion: Therapy for acute exacerbation of COPD using a combination of ipratropium bromide/salbutamol sulfate as a preventive therapy is in line with the GOLD guidelines.

Original languageEnglish
Pages (from-to)224-227
Number of pages4
JournalPharmacy Education
Volume23
Issue number4
DOIs
Publication statusPublished - 10 Oct 2023

Keywords

  • Acute exacerbation
  • Bronchodilator
  • Chronic obstructive pulmonary disease
  • Chronic respiratory disease

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