This study aims to prove the effectiveness of RBM-MSC therapy to reduce the expression of Vascular Endhotel Growth Factor in carbon black-induced white Rattus norvegicus. This study used 48 female rats divided into 2 treatment groups with different ages pregnancy in 8 replications. This study was induced with a carbon black dose of 532mg/m3and treated with RBM-MSC dose 1x106cells/0.1ml intravenously. The results of the study of induction of carbon black at days 6-11 and days 6-17 showed differences in the VEGF expression between the control and treatment groups. The conclusion of this study has not been able to reduce the expression of VEGF, because shorter times optimally for RBM-MSC.

Original languageEnglish
Pages (from-to)25-27
Number of pages3
JournalIndian Veterinary Journal
Issue number12
Publication statusPublished - 2019


  • (RBM-MSC) - rat
  • (VEGF)
  • Carbon black


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