The Potency of Asiatic Acid in Reducing Fibrosis after Strabismus Surgery via Type-2 Immunity Pathway: Review

Harris Kristanto Gunawan, Evelyn Komaratih, Rozalina Loebis

Research output: Contribution to journalReview articlepeer-review

Abstract

Strabismus affects functionally, such as reducing binocular vision and causing diplopia, and also affects psychologically. Surgery is required for most strabismus cases, but excessive fibrosis can cause recurrent strabismus. Type 2 immunity is involved in the wound healing, and excessive inflammation from type 2 immunity can lead to excessive fibrosis. An extract from Centella asiatica, asiatic acid, has been studied that it can reduce inflammation and fibrosis in several organs. Asiatic acid can reduce inflammation caused by type 2 immunity by reducing IL-4. Asiatic acid has the potential to reduce fibrosis after strabismus surgery.

Original languageEnglish
Article number236409
JournalJournal of Drug and Alcohol Research
Volume13
Issue number9
DOIs
Publication statusPublished - 2024

Keywords

  • Asiatic acid
  • Centella asiatica
  • Strabismus surgery
  • Type 2 immunity
  • Wound healing

Fingerprint

Dive into the research topics of 'The Potency of Asiatic Acid in Reducing Fibrosis after Strabismus Surgery via Type-2 Immunity Pathway: Review'. Together they form a unique fingerprint.

Cite this