TY - JOUR
T1 - The outcomes of infants with HIV infected mother in a tertiary hospital in Indonesia
AU - Ningtiar, Hapsari Widya
AU - Kartina, Leny
AU - Puspitasari, Dwiyanti
AU - Husada, Dominicus
AU - Basuki, Parwati Setiono
AU - Ismoedijanto,
N1 - Publisher Copyright:
© 2019, Indian Journal of Public Health Research and Development. All rights reserved.
PY - 2019/8
Y1 - 2019/8
N2 - Background: Infant from HIV mother face the risk of HIV infection. Effective prevention on mother-to-child transmission (PMTCT) program increasing the number of uninfected infants in East Java Indonesia. This study describes the outcomes of infants with HIV mother in Dr. Soetomo Hospital, a tertiary referral hospital in East Java, related to outcome (infectious morbidity, nutritional status, immunodeficiency status, growth/development, and incidence of anemia). Method: This cross-sectional study analyzed 0-18 months infant and HIV mother pairs at HIV outpatient clinic Dr. Soetomo General Hospital from January to April 2017. The data were collected and analyzed using Fisher’s exact test and chi-square test with P<0.05. Results: Fourty HIV-infected mothers and infants pairs were analyzed, separated into two groups positive (3 infants) and negative (37 infants) Anti HIV PCR. There were 19 male. Age distribution (6 weeks-5 months 40%; 6-11 months 47.5%; 12-18 months 12.5%). Five percent were born prematurely, 77.5% infant has normal birth-weight. Only 2.5% were fed breast milk, AZT-cotrimoxazole were given to 87.5% infant while the rest received AZT/3TC/NVP. Immunizations of the infants were mostly (60%) up to date. Infectious morbidity (P=0.433), WAZ-score (P=0.666), LAZ-score (P=0,973), WLZ-score (P=0.219) and incidence of anemia (P=0.548) were not significant differences between groups. The development test using DDST II (P=0,001), as well as immunodeficiency status [presence of immunodeficiency (P<0.001)] was significantly different between groups. Conclusion: There were significant effects of HIV exposed on the development and immunodeficiency status in 0-18 months infant.
AB - Background: Infant from HIV mother face the risk of HIV infection. Effective prevention on mother-to-child transmission (PMTCT) program increasing the number of uninfected infants in East Java Indonesia. This study describes the outcomes of infants with HIV mother in Dr. Soetomo Hospital, a tertiary referral hospital in East Java, related to outcome (infectious morbidity, nutritional status, immunodeficiency status, growth/development, and incidence of anemia). Method: This cross-sectional study analyzed 0-18 months infant and HIV mother pairs at HIV outpatient clinic Dr. Soetomo General Hospital from January to April 2017. The data were collected and analyzed using Fisher’s exact test and chi-square test with P<0.05. Results: Fourty HIV-infected mothers and infants pairs were analyzed, separated into two groups positive (3 infants) and negative (37 infants) Anti HIV PCR. There were 19 male. Age distribution (6 weeks-5 months 40%; 6-11 months 47.5%; 12-18 months 12.5%). Five percent were born prematurely, 77.5% infant has normal birth-weight. Only 2.5% were fed breast milk, AZT-cotrimoxazole were given to 87.5% infant while the rest received AZT/3TC/NVP. Immunizations of the infants were mostly (60%) up to date. Infectious morbidity (P=0.433), WAZ-score (P=0.666), LAZ-score (P=0,973), WLZ-score (P=0.219) and incidence of anemia (P=0.548) were not significant differences between groups. The development test using DDST II (P=0,001), as well as immunodeficiency status [presence of immunodeficiency (P<0.001)] was significantly different between groups. Conclusion: There were significant effects of HIV exposed on the development and immunodeficiency status in 0-18 months infant.
KW - HIV-exposed infants
KW - Outcomes
KW - Prevention on mother-to-child transmission/PMTCT
UR - http://www.scopus.com/inward/record.url?scp=85073762477&partnerID=8YFLogxK
U2 - 10.5958/0976-5506.2019.02158.2
DO - 10.5958/0976-5506.2019.02158.2
M3 - Article
AN - SCOPUS:85073762477
SN - 0976-0245
VL - 10
SP - 2058
EP - 2062
JO - Indian Journal of Public Health Research and Development
JF - Indian Journal of Public Health Research and Development
IS - 8
ER -