The impact of ellagic acid and bovine bone xenograft combination on arterial and cerebral blood pressure

Introduction: Arterial hypertension, commonly known as high blood pressure, is a chronic medical condition characterized by elevated pressure in the arteries. It often leads to various complications, including cardio-vascular diseases and stroke. The brain, being highly sensitive to changes in blood pressure, is particularly vulnerable to the effects of hypertension. Objective: This study aims to investigate the relationship between arterial hypertension and its impact on cerebral blood flow regulation. Materials and Methods: A comprehensive review of relevant literature was conducted to analyze the mechanisms underlying the association between arterial hypertension and cerebral blood flow regulation. Studies focusing on the effects of hypertension on cerebral autoregulation, endothelial func-tion, and cerebral vascular resistance were included. Results: Arterial hypertension disrupts the normal regulatory mechanisms of cerebral blood flow, lead-ing to impaired cerebral autoregulation and endothelial dysfunction. Chronic hypertension results in structural alterations in the cerebral vasculature, such as arterio-sclerosis and arteriolar remodeling, further compromis-ing cerebral blood flow regulation. Conclusion: The findings of this review highlight the detrimental effects of arterial hypertension on cerebral blood flow regula-tion. Understanding these mechanisms is crucial for developing effective strategies to prevent and manage hypertension-related cerebral complications.