The histopathology of antique ark’s mantle (Anadara antiquata) post-depuration with the shells’ filtration

Research output: Contribution to journalArticlepeer-review


Cockles are marine organisms which have the character of filter feeders so that heavy metals can be neutralized naturally through their shells. However, not all heavy metals can be neutralized, so depuration needs to be done. After depuration, histopathological analysis is needed to determine the condition of the soft tissue of the shells so that the disease can be diagnosed through structural changes that occur in the organs that are the main target of pollutants. This study aims to determine the histopathology of antique ark’s mantle (Anadara antiquata) after post-depuration with the filtration of the cockles’ shells. This research method applies an experimental method with scoring histological damage to antique ark’s mantle that ranges from 0 to 3, depending on the level and extent of the changes that occur. After that, the distribution of normal and non-homogeneous data was obtained, and then the Kruskal-Wallis non-parametric test was conducted. The main parameter is the histopathology of the antique ark’s mantle. Supporting parameters include water quality, namely temperature, dissolved oxygen (DO), nitrate, nitrite, ammonia, salinity, levels of heavy metals Pb and Cd, total suspended solid (TSS) and total dissolved solid (TDS). The results of the Kruskal-Wallis statistical analysis shows no significant difference between treatments P0 (Control), P1 (Filter 25%), P2 (Filter 50%), P3 (Filter 75%), and P4 (Filter 100%). The histopathological features of the antique ark’s mantle organ tissue found were edema, hyperplasia, necrosis, and atrophy.

Original languageEnglish
Pages (from-to)250-260
Number of pages11
JournalAACL Bioflux
Issue number1
Publication statusPublished - 2020


  • Antique ark (Anadara antiquata)
  • Filter feeder
  • Histopathology
  • Mantle


Dive into the research topics of 'The histopathology of antique ark’s mantle (Anadara antiquata) post-depuration with the shells’ filtration'. Together they form a unique fingerprint.

Cite this