TY - JOUR
T1 - The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin e for Wrinkles, Spots, and Pores in Photoaging
AU - Rahmadewi, Rahmadewi
AU - Retha, Retha
AU - Pitasari, Dyah Ayu
AU - Kusumastanto, Vidyani Adiningtyas
AU - Ardhaninggar, Agatha Anindita Ayu
AU - Citrashanty, Irmadita
AU - Sari, Maylita
AU - Umborowati, Menul Ayu
AU - Prakoeswa, Cita Rosita Sigit
N1 - Publisher Copyright:
© 2020 Rahmadewi et al.
PY - 2020
Y1 - 2020
N2 - Background. It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. This promises an option for photoaging therapy in the future. Materials and Methods. Sixty women with photoaged skins were involved in this experimental study. They were then divided into two groups. The treatment group received a topical combination of AMSC-MP and vitamin E, and the control group received AMSC-MP alone after fractional CO2 laser. The treatment was repeated three times. Result. The Janus assessment results showed a significant difference in pores in the third observation, and the average pore improvements in the treatment group were better than the control group. Wrinkle, UV spot, and polar spot did not show any significant difference. Conclusion. A combination of the amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as LADD only improves pores in photoaged skins.
AB - Background. It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. This promises an option for photoaging therapy in the future. Materials and Methods. Sixty women with photoaged skins were involved in this experimental study. They were then divided into two groups. The treatment group received a topical combination of AMSC-MP and vitamin E, and the control group received AMSC-MP alone after fractional CO2 laser. The treatment was repeated three times. Result. The Janus assessment results showed a significant difference in pores in the third observation, and the average pore improvements in the treatment group were better than the control group. Wrinkle, UV spot, and polar spot did not show any significant difference. Conclusion. A combination of the amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as LADD only improves pores in photoaged skins.
UR - http://www.scopus.com/inward/record.url?scp=85091450826&partnerID=8YFLogxK
U2 - 10.1155/2020/1584541
DO - 10.1155/2020/1584541
M3 - Article
AN - SCOPUS:85091450826
SN - 1687-6105
VL - 2020
JO - Dermatology Research and Practice
JF - Dermatology Research and Practice
M1 - 1584541
ER -