The effects of yoga on blood pressure, cortisol, and TNF-α among mothers at risk of preeclampsia

Hamimatus Zainiyah, Bambang Purwanto, Raden Argarini, Mukhoirotin Mukhoirotin, Ernawati Ernawati

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Preeclampsia is the most common disorder in pregnancy and causes maternal and fetal morbidity and mortality. Its pathophysiology is related to inflammatory factors. This study aimed to analyze the effects of yoga on blood pressure, cortisol levels, and serum TNF-α levels in mothers at high risk of preeclampsia. An experimental pre-test, post-test control group design was conducted among 46 mothers at risk for preeclampsia. Participants at 9-16 weeks of gestation were randomly divided into the yoga practice and control groups. All groups received standard treatment, and the yoga practice group performed twenty yoga exercises over four weeks. Cortisol, serum TNF-α, and blood pressure levels were measured before and after treatment. A chemiluminescent microparticle immunoassay and enzyme-linked immunosorbent assay analyzed cortisol and TNF-α levels, respectively. Blood pressure was measured using an aneroid sphygmomanometer. Cortisol levels did not differ before (16.24±6.81 ug/dL) and after a treatment course (15.58±5.63 ug/dL) in both groups. Similarly, TNF-α levels did not differ before (184.42±113.27 ng/L) and following a training course (179.47±111.93 ng/L). The average systolic and diastolic blood pressures in the control group were higher at the end of the treatment (p=0,006 and p=0.021, respectively). In comparison, the yoga group's systolic and diastolic blood pressures were lower (p=0.007 and p=0.002, respectively).Four weeks of yoga succeeded in improving systolic and diastolic blood pressure and reducing the mean levels of cortisol and serum TNF-α in mother at high risk of preeclampsia, but not significantly.

Original languageEnglish
Pages (from-to)1369-1378
Number of pages10
JournalJournal of Medicinal and Pharmaceutical Chemistry Research
Volume7
Issue number7
DOIs
Publication statusPublished - Jul 2025

Keywords

  • blood pressure
  • cortisol
  • maternal mortality
  • pre-eclampsia
  • TNF-α
  • Yoga

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