TY - JOUR
T1 - The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure
T2 - An in vivo study
AU - Astuti, Suryani Dyah
AU - Victory, Vivi Sumanti
AU - Mahmud, Amalia Fitriana
AU - Putra, Alfian Pramudita
AU - Winarni, Dwi
N1 - Funding Information:
The author would like to say thank you to Ministry of Research, Technology and Higher Education with Grant number [No. 007/F1/PPK.2/Kp/V/2019].
Publisher Copyright:
© 2019 Network for the Veterinarians of Bangladesh.
PY - 2019
Y1 - 2019
N2 - Objective: The aim of this study is to determine the effect of laser diode as an alternative treatment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group C-L- (control group, no treatment), Group C+L- (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored. Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule. Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells.
AB - Objective: The aim of this study is to determine the effect of laser diode as an alternative treatment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C. Materials and Methods: The samples were divided into three groups, namely, Group C-L- (control group, no treatment), Group C+L- (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored. Results: Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule. Conclusion: The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells.
KW - Laser diode
KW - Liver dysfunction
KW - Mus musculus
KW - Photobiomodulation
UR - http://www.scopus.com/inward/record.url?scp=85075328948&partnerID=8YFLogxK
U2 - 10.5455/javar.2019.f374
DO - 10.5455/javar.2019.f374
M3 - Article
AN - SCOPUS:85075328948
SN - 2311-7710
VL - 6
SP - 499
EP - 505
JO - Journal of Advanced Veterinary and Animal Research
JF - Journal of Advanced Veterinary and Animal Research
IS - 4
ER -