Abstract

This study investigates the impact of maternal obesity on labor outcomes, specifically focusing on the rates and outcomes of labor induction. Indonesia ranks first in Southeast Asia for obesity prevalence, with over 30% of its adult population classified as overweight or obese according to the World Health Organization's (WHO) body mass index (BMI) criteria (BMI > 25 kg/m² for overweight and BMI > 30 kg/m² for obesity). Obesity during pregnancy significantly raises the risk of maternal and fetal complications, including thromboembolism, preeclampsia, and eclampsia, and is associated with increased rates of labor induction and induction failure. This study addresses the relationship between maternal obesity, labor induction outcomes, and specific complications such as fetal macrosomia, which is more prevalent among offspring of obese mothers and contributes to higher risks of induction failure. Furthermore, maternal obesity influences placental weight, structure, and function, which may affect pregnancy progression and increase the likelihood of post-term pregnancy in the absence of induction. The findings aim to inform obstetric management strategies for obese pregnant women, contributing to improved maternal and fetal health outcomes.

Original languageEnglish
Pages (from-to)1503-1512
Number of pages10
JournalJournal of Medicinal and Pharmaceutical Chemistry Research
Volume7
Issue number7
DOIs
Publication statusPublished - Jul 2025

Keywords

  • Obesity
  • induction
  • labor
  • pregnancy

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