TY - JOUR
T1 - The differences of risk factors and outcomes of pregnancy with obesity who had failed and successful induction of labor in 2023
AU - Nabilah, Huwaida
AU - Akbar, Muhammad Ilham Aldika
AU - Joewono, Hermanto Tri
N1 - Publisher Copyright:
© 2025 by SPC.
PY - 2025/7
Y1 - 2025/7
N2 - This study investigates the impact of maternal obesity on labor outcomes, specifically focusing on the rates and outcomes of labor induction. Indonesia ranks first in Southeast Asia for obesity prevalence, with over 30% of its adult population classified as overweight or obese according to the World Health Organization's (WHO) body mass index (BMI) criteria (BMI > 25 kg/m² for overweight and BMI > 30 kg/m² for obesity). Obesity during pregnancy significantly raises the risk of maternal and fetal complications, including thromboembolism, preeclampsia, and eclampsia, and is associated with increased rates of labor induction and induction failure. This study addresses the relationship between maternal obesity, labor induction outcomes, and specific complications such as fetal macrosomia, which is more prevalent among offspring of obese mothers and contributes to higher risks of induction failure. Furthermore, maternal obesity influences placental weight, structure, and function, which may affect pregnancy progression and increase the likelihood of post-term pregnancy in the absence of induction. The findings aim to inform obstetric management strategies for obese pregnant women, contributing to improved maternal and fetal health outcomes.
AB - This study investigates the impact of maternal obesity on labor outcomes, specifically focusing on the rates and outcomes of labor induction. Indonesia ranks first in Southeast Asia for obesity prevalence, with over 30% of its adult population classified as overweight or obese according to the World Health Organization's (WHO) body mass index (BMI) criteria (BMI > 25 kg/m² for overweight and BMI > 30 kg/m² for obesity). Obesity during pregnancy significantly raises the risk of maternal and fetal complications, including thromboembolism, preeclampsia, and eclampsia, and is associated with increased rates of labor induction and induction failure. This study addresses the relationship between maternal obesity, labor induction outcomes, and specific complications such as fetal macrosomia, which is more prevalent among offspring of obese mothers and contributes to higher risks of induction failure. Furthermore, maternal obesity influences placental weight, structure, and function, which may affect pregnancy progression and increase the likelihood of post-term pregnancy in the absence of induction. The findings aim to inform obstetric management strategies for obese pregnant women, contributing to improved maternal and fetal health outcomes.
KW - Obesity
KW - induction
KW - labor
KW - pregnancy
UR - http://www.scopus.com/inward/record.url?scp=85210073342&partnerID=8YFLogxK
U2 - 10.48309/jmpcr.2025.483420.1471
DO - 10.48309/jmpcr.2025.483420.1471
M3 - Review article
AN - SCOPUS:85210073342
SN - 2981-0221
VL - 7
SP - 1503
EP - 1512
JO - Journal of Medicinal and Pharmaceutical Chemistry Research
JF - Journal of Medicinal and Pharmaceutical Chemistry Research
IS - 7
ER -