The self-care ability of patients with hypertension is still relatively low. One of the contributing factors is the lack of self-regulation to carry out recommended health behaviors. This will result in uncontrolled blood pressure and an increased risk of complications. The purpose of this study was to develop self regulation model based on belief to improve self-care abilities in people with hypertension. The study design used explanatory surveys. The samples were 225 people with hypertension with systolic blood pressure >160 mmHg taken by multistage random sampling technique. The research variables include social support factors, health services factors, interpretations, emotional responses, beliefs, coping, self-efficacy, coping, self-care abilities and hypertension status. The research instrument used a questionnaire and a digital sphygmomanometer. Data analysis was performed by using Structural Equation Modeling - Partial Least Squares (SEM - PLS). The results showed that the process of self-regulation in patients with hypertension is formed by belief, which can affect self-care ability. Belief directly affects the coping and emotional response of sufferers. Self-efficacy plays a major role in forming coping. In addition, it was found that interpretation was formed by the social support and health services factor. The ability of self-care affects the hypertension status of patients both in blood pressure and pulse. The implication of this result is the need to strengthen the belief of patients made by health workers so that hypertension sufferers can optimally fulfill their care needs appropriately so that blood pressure can be controlled properly.