TY - GEN
T1 - The design of 3D printed polylactic acid (PLA) morphology with coating of chitosan
AU - Hikmawati, Dyah
AU - Zulaihah, Siti
AU - Aminatun,
N1 - Publisher Copyright:
© 2020 Author(s).
PY - 2020/12/9
Y1 - 2020/12/9
N2 - Bone implant biomaterials require surface morphology with a material content that facilitates osteointegration, thereby supporting cell proliferation and regeneration and avoiding inflammation due to bacterial activity. In this research, the surface morphology design was carried out in the form of pyramid, rhombicuboctahedron and icosahedron through 3D printing using FDM (Fused Deposition Modeling) method using PLA (Polylactide Acid) as the filament. Chitosan, which functions as an antibacterial, is used to coat the surface of the 3D printed PLA using dip-coating method with variations of 1%, 2%, 3%. The characterizations done are FTIR test, SEM test, porosity test, contact angle test, degradation test, and antibacterial test. FTIR test results showed the presence of chitosan clusters which are able to coat PLA samples successfully. SEM results showed the surface morphology before and after chitosan coating. The pyramid design has the pore size of 1,111 μm-1,334 μm which is compatible to the macropore size for bone reconstruction, with porosity values of 48%-53% which also agrees to a bone porosity values. On 3% chitosan coating, it is hydrophilic with a contact angle of 20.15° which decreases immediately after, antibacterial test results showed an inhibition zone of 2.48 mm. The degradation test results prove the sample still survives until the 4th week with a mass reduction of 2.2%.
AB - Bone implant biomaterials require surface morphology with a material content that facilitates osteointegration, thereby supporting cell proliferation and regeneration and avoiding inflammation due to bacterial activity. In this research, the surface morphology design was carried out in the form of pyramid, rhombicuboctahedron and icosahedron through 3D printing using FDM (Fused Deposition Modeling) method using PLA (Polylactide Acid) as the filament. Chitosan, which functions as an antibacterial, is used to coat the surface of the 3D printed PLA using dip-coating method with variations of 1%, 2%, 3%. The characterizations done are FTIR test, SEM test, porosity test, contact angle test, degradation test, and antibacterial test. FTIR test results showed the presence of chitosan clusters which are able to coat PLA samples successfully. SEM results showed the surface morphology before and after chitosan coating. The pyramid design has the pore size of 1,111 μm-1,334 μm which is compatible to the macropore size for bone reconstruction, with porosity values of 48%-53% which also agrees to a bone porosity values. On 3% chitosan coating, it is hydrophilic with a contact angle of 20.15° which decreases immediately after, antibacterial test results showed an inhibition zone of 2.48 mm. The degradation test results prove the sample still survives until the 4th week with a mass reduction of 2.2%.
UR - http://www.scopus.com/inward/record.url?scp=85097979976&partnerID=8YFLogxK
U2 - 10.1063/5.0034911
DO - 10.1063/5.0034911
M3 - Conference contribution
AN - SCOPUS:85097979976
T3 - AIP Conference Proceedings
BT - 2nd International Conference on Physical Instrumentation and Advanced Materials 2019
A2 - Trilaksana, Herri
A2 - Harun, Sulaiman Wadi
A2 - Shearer, Cameron
A2 - Yasin, Moh
PB - American Institute of Physics Inc.
T2 - 2nd International Conference on Physical Instrumentation and Advanced Materials, ICPIAM 2019
Y2 - 22 October 2019
ER -