The beneficial effect of Aloe vera in skin barrier function improvement: A double-blind randomized trial of Madurese batik craftswomen

Background Exposure to chemicals in batik process increases the risk of skin barrier disruption in batik craftswomen. Methods In the control group, the stratum corneum hydration was significantly increased at the evaluation of the 2nd week (P=0.045; CI 95%) and the 4th week (P=0.010; CI 95%). In the experimental group there was a significant decrease in TEWL value at the 2nd week evaluation (P=0.004; CI 95%), a significant increase in stratum corneum hydration at the 2nd week (P <0.001; CI 95%) and 4th week evaluation (P<0.001; CI 95%), and significant skin pH at 4th week (P=0.014; CI 95%). Results In the control group, the stratum corneum hydration was significantly increased at the evaluation of the 2nd week and the 4th week. In the experimental group there was a significant decrease in TEWL value at the 2nd week evaluation, a significant increase in stratum corneum hydration at the 2nd week and 4th week evaluation, and significant skin pH at 4th week. Conclusion Aloe vera benefits in improving the physiological function of the skin in Madurese batik craftswomen