The bacterial profile and antibiotic resistance among patients with urinary tract infection in Surabaya, Indonesia

Introduction: Urinary tract infections (UTIs) are mainly caused by microorganisms and occur in the urinary tract to the kidneys. Management of UTI related to antibiotic therapy, rational use of antibiotics is needed to prevent bacterial resistance. This objective of this study is to determine the pattern of bacteria, resistance and sensitivity to antibiotics in patients with UTI at Islamic Hospital Surabaya, Indonesia, in January 2019 - March 2020. Methods: This was an observational analytical study using a cross-sectional approach. Data were obtained from UTI patients' urine culture results and medical records. Results: There were 33 UTI patients, but only 22 patients (66,7%) showed positive to urine cultures with several types of bacteria. This study obtained Escherichia coli (24,0%) and Enterococcus sp. (24,0%) as the most bacteria causing UTI. These microorganisms showed resistance to Trimethoprim-sulfamethoxazole but sensitive against the antibiotics Fosfomycin, Nitrofurantoin, Ciprofloxacin, Levofloxacin, beta-lactam antibiotics (eg. Piperacillin-tazobactam, Amoxicillin-clavulanate). Conclusion: Our results showed that Escherichia coli and Enterococcus sp. as frequent bacterial found among UTI patients. Our results urged that initial screening for resistance/sensitivity pattern for antibiotics could help to choose suitable treatment for UTI patients.