TY - JOUR
T1 - Synthetic studies on natural isocoumarins and isocarbostyril derivatives having an alkyl substituent at the 3-position
T2 - Total synthesis of scoparines A and B, and ruprechstyril
AU - Rudyanto, Marcellino
AU - Kobayashi, Koichi
AU - Honda, Toshio
PY - 2009
Y1 - 2009
N2 - Two isocoumarins, scoparines A and B, having n-propyl group at the 3-position, and a new isocarbostyril, ruprechstyril, bearing n-pentyl substituent at the 3-position were synthesized via Sonogashira coupling of the corresponding aromatic halides and alkynes, followed by regioselective 6-endo-dig cyclization.
AB - Two isocoumarins, scoparines A and B, having n-propyl group at the 3-position, and a new isocarbostyril, ruprechstyril, bearing n-pentyl substituent at the 3-position were synthesized via Sonogashira coupling of the corresponding aromatic halides and alkynes, followed by regioselective 6-endo-dig cyclization.
KW - 6-endo-dig Cyclization
KW - Isocoumarin
KW - Ruprechstyril
KW - Scoparine
KW - Sonogashira Coupling
UR - http://www.scopus.com/inward/record.url?scp=67651125024&partnerID=8YFLogxK
U2 - 10.3987/COM-08-S(D)40
DO - 10.3987/COM-08-S(D)40
M3 - Article
AN - SCOPUS:67651125024
SN - 0385-5414
VL - 79
SP - 753
EP - 764
JO - Heterocycles
JF - Heterocycles
IS - C
ER -