Synthetic strategies and biomedical applications of I-III-VI ternary quantum dots

Wubshet Mekonnen Girma, Mochamad Zakki Fahmi, Adi Permadi, Mulu Alemayehu Abate, Jia Yaw Chang

Research output: Contribution to journalReview articlepeer-review

96 Citations (Scopus)

Abstract

Surface modified and bioconjugated quantum dots (QDs) are of central importance in biomedical applications. In this regard, particularly I-III-VI QDs are of specific interest for biosensors, multimodal imaging, chemotherapy and for phototherapy in theranostic applications. Surface modification allows management of the physico-chemical properties, biocompatibility, and pharmacological properties. This review is anticipated to provide an introduction to new researchers about I-III-VI type QDs relating to their synthesis, optical properties, surface modification, bioconjugation, and their applications in biosensors, biological imaging, drug delivery, photothermal therapy and photodynamic therapy. We also highlight introducing magnetic metals and nanoparticles to these QDs for multimodal imaging applications and have addressed toxicity related issues. Finally, we summarize the results obtained and give a short outlook on future directions of I-III-VI based QDs for biomedical applications.

Original languageEnglish
Pages (from-to)6193-6216
Number of pages24
JournalJournal of Materials Chemistry B
Volume5
Issue number31
DOIs
Publication statusPublished - 2017

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