Surface Modification of Nanocarriers for Specific Cell Targeting for Better Therapeutic Effect

Doniya Milani, Umi Athiyah, Dewi Melani Hariyadi, Yashwant V. Pathak

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)

Abstract

Nanocarriers may potentially change the future of medicine. These nano-sized drug delivery vesicles have been employed to enhance the efficacy and safety of different therapeutic agents. Specifically designed to localize in target sites, nanocarriers have the ability to increase cellular uptake while decreasing toxicity. Surface-modified nanocarriers have the potential to overcome several biological barriers, thus further improving site specificity while also avoiding endosomal sequestration and degradation of the cargo. In this review, surface modifications aimed at cell targeting for better drug delivery are discussed.

Original languageEnglish
Title of host publicationSurface Modification of Nanoparticles for Targeted Drug Delivery
PublisherSpringer International Publishing
Pages355-368
Number of pages14
ISBN (Electronic)9783030061159
ISBN (Print)9783030061142
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Cellular targeting
  • Drug delivery
  • Drug targeting
  • Nanocarriers
  • Nanomedicine
  • Organelle targeting
  • Surface modifications

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