Abstract
Nanocarriers may potentially change the future of medicine. These nano-sized drug delivery vesicles have been employed to enhance the efficacy and safety of different therapeutic agents. Specifically designed to localize in target sites, nanocarriers have the ability to increase cellular uptake while decreasing toxicity. Surface-modified nanocarriers have the potential to overcome several biological barriers, thus further improving site specificity while also avoiding endosomal sequestration and degradation of the cargo. In this review, surface modifications aimed at cell targeting for better drug delivery are discussed.
Original language | English |
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Title of host publication | Surface Modification of Nanoparticles for Targeted Drug Delivery |
Publisher | Springer International Publishing |
Pages | 355-368 |
Number of pages | 14 |
ISBN (Electronic) | 9783030061159 |
ISBN (Print) | 9783030061142 |
DOIs | |
Publication status | Published - 1 Jan 2019 |
Keywords
- Cellular targeting
- Drug delivery
- Drug targeting
- Nanocarriers
- Nanomedicine
- Organelle targeting
- Surface modifications