TY - JOUR
T1 - Superior possibilities and upcoming horizons for nanoscience in COVID-19
T2 - noteworthy approach for effective diagnostics and management of SARS-CoV-2 outbreak
AU - Bhattacharjee, Bedanta
AU - Ikbal, Abu Md Ashif
AU - Farooqui, Atika
AU - Sahu, Ram Kumar
AU - Ruhi, Sakina
AU - Syed, Ayesha
AU - Miatmoko, Andang
AU - Khan, Danish
AU - Khan, Jiyauddin
N1 - Publisher Copyright:
© 2023, Institute of Chemistry, Slovak Academy of Sciences.
PY - 2023/8
Y1 - 2023/8
N2 - The outbreak of COVID-19 has caused great havoc and affected many parts of the world. It has imposed a great challenge to the medical and health fraternity with its ability to continue mutating and increasing the transmission rate. Some challenges include the availability of current knowledge of active drugs against the virus, mode of delivery of the medicaments, its diagnosis, which are relatively limited and do not suffice for further prognosis. One recently developed drug delivery system called nanoparticles is currently being utilized in combating COVID-19. This article highlights the existing methods for diagnosis of COVID-19 such as computed tomography scan, reverse transcription-polymerase chain reaction, nucleic acid sequencing, immunoassay, point-of-care test, detection from breath, nanotechnology-based bio-sensors, viral antigen detection, microfluidic device, magnetic nanosensor, magnetic resonance platform and internet-of-things biosensors. The latest detection strategy based on nanotechnology, biosensor, is said to produce satisfactory results in recognizing SARS-CoV-2 virus. It also highlights the successes in the research and development of COVID-19 treatments and vaccines that are already in use. In addition, there are a number of nanovaccines and nanomedicines currently in clinical trials that have the potential to target COVID-19.
AB - The outbreak of COVID-19 has caused great havoc and affected many parts of the world. It has imposed a great challenge to the medical and health fraternity with its ability to continue mutating and increasing the transmission rate. Some challenges include the availability of current knowledge of active drugs against the virus, mode of delivery of the medicaments, its diagnosis, which are relatively limited and do not suffice for further prognosis. One recently developed drug delivery system called nanoparticles is currently being utilized in combating COVID-19. This article highlights the existing methods for diagnosis of COVID-19 such as computed tomography scan, reverse transcription-polymerase chain reaction, nucleic acid sequencing, immunoassay, point-of-care test, detection from breath, nanotechnology-based bio-sensors, viral antigen detection, microfluidic device, magnetic nanosensor, magnetic resonance platform and internet-of-things biosensors. The latest detection strategy based on nanotechnology, biosensor, is said to produce satisfactory results in recognizing SARS-CoV-2 virus. It also highlights the successes in the research and development of COVID-19 treatments and vaccines that are already in use. In addition, there are a number of nanovaccines and nanomedicines currently in clinical trials that have the potential to target COVID-19.
KW - Biosensor
KW - COVID-19
KW - Computer tomography
KW - Nanovaccines
KW - Polymerase chain reaction
KW - SARS-CoV-2 virus
UR - http://www.scopus.com/inward/record.url?scp=85151730851&partnerID=8YFLogxK
U2 - 10.1007/s11696-023-02795-3
DO - 10.1007/s11696-023-02795-3
M3 - Review article
AN - SCOPUS:85151730851
SN - 0366-6352
VL - 77
SP - 4107
EP - 4130
JO - Chemical Papers
JF - Chemical Papers
IS - 8
ER -