A-nor steroids from the marine sponge, Clathria species

Idin Sahidin, Carla Wulandari Sabandar, Wahyuni, Rini Hamsidi, Muhammad Hajrul Malaka, Baru Sadarun, La Ode Aslan

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Chemical compounds classified as A-nor steroids (1–4) were isolated from a marine sponge of the Clathria sp., collected from Southeast Sulawesi, Indonesia. Of these, one new compound, clathruhoate (1) was elucidated as 3β-(butyryloxymethyl)-A-nor-5α-cholestane. All compounds were obtained using silica gel chromatography techniques and their structures were determined based on 1D and 2D NMR spectroscopic measurements and comparison with values from literature. Meanwhile, all compounds were inactive for antimicrobial activity.

Original languageEnglish
Pages (from-to)375-382
Number of pages8
JournalMalaysian Journal of Analytical Sciences
Volume22
Issue number3
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • 3β-(Butyryloxymethyl)-A-nor-5α-cholestane
  • A-nor steroid
  • Clathria sp
  • Marine sponge

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