Splenic vein thrombosis in cirrhosis of the liver: A rare case

Arina Mana Sikana; Husin Thamrin

doi:10.1016/j.amsu.2022.104439

Splenic vein thrombosis in cirrhosis of the liver: A rare case

Arina Mana Sikana, Husin Thamrin

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Splenic Vein Thrombosis (SpVT) in a young patient with non-hepatitis B and C liver cirrhosis is an infrequent case generating hemorrhagic manifestations. Herein we report a 28-year-old man presenting with hematemesis, melena, and features of liver cirrhosis. Hematemesis, melena, and ascites resolve following a conservative treatment. Abdominal ultrasound confirmed portal hypertension. Serial endoscopy on day 14, 17 and 1-month evaluation showed grade II-III esophageal varices and severe hypertensive portal gastropathy. Abdominal CT scan with contrast within 1 week after discharge revealed thrombus along ± 5.8 cm, splenomegaly with dilated splenic vein, dilatation and tourtosity of the left gastric vein and visualized distal esophageal vein. Liver biopsy 2 months after hospitalization showed hepatocytes with extensive hydropic degeneration with fibrosis (F3).

Original language	English
Article number	104439
Journal	Annals of Medicine and Surgery
Volume	81
DOIs	https://doi.org/10.1016/j.amsu.2022.104439
Publication status	Published - Sept 2022

Keywords

Liver biopsy
Liver cirrhosis
Portal hypertension
Thrombosis
Treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.amsu.2022.104439

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@article{d528bd1b54524e9fb25f8763e0da84b2,

title = "Splenic vein thrombosis in cirrhosis of the liver: A rare case",

abstract = "Splenic Vein Thrombosis (SpVT) in a young patient with non-hepatitis B and C liver cirrhosis is an infrequent case generating hemorrhagic manifestations. Herein we report a 28-year-old man presenting with hematemesis, melena, and features of liver cirrhosis. Hematemesis, melena, and ascites resolve following a conservative treatment. Abdominal ultrasound confirmed portal hypertension. Serial endoscopy on day 14, 17 and 1-month evaluation showed grade II-III esophageal varices and severe hypertensive portal gastropathy. Abdominal CT scan with contrast within 1 week after discharge revealed thrombus along ± 5.8 cm, splenomegaly with dilated splenic vein, dilatation and tourtosity of the left gastric vein and visualized distal esophageal vein. Liver biopsy 2 months after hospitalization showed hepatocytes with extensive hydropic degeneration with fibrosis (F3).",

keywords = "Liver biopsy, Liver cirrhosis, Portal hypertension, Thrombosis, Treatment",

author = "Sikana, {Arina Mana} and Husin Thamrin",

note = "Funding Information: This work is supported by Hemato-oncology and Internist of Internal Department, Medical Faculty, Airlangga University, Dr. Soetomo General Hospital Surabaya, Indonesia. Publisher Copyright: {\textcopyright} The Authors",

year = "2022",

month = sep,

doi = "10.1016/j.amsu.2022.104439",

language = "English",

volume = "81",

journal = "Annals of Medicine and Surgery",

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}

TY - JOUR

T1 - Splenic vein thrombosis in cirrhosis of the liver

T2 - A rare case

AU - Sikana, Arina Mana

AU - Thamrin, Husin

N1 - Funding Information: This work is supported by Hemato-oncology and Internist of Internal Department, Medical Faculty, Airlangga University, Dr. Soetomo General Hospital Surabaya, Indonesia. Publisher Copyright: © The Authors

PY - 2022/9

Y1 - 2022/9

N2 - Splenic Vein Thrombosis (SpVT) in a young patient with non-hepatitis B and C liver cirrhosis is an infrequent case generating hemorrhagic manifestations. Herein we report a 28-year-old man presenting with hematemesis, melena, and features of liver cirrhosis. Hematemesis, melena, and ascites resolve following a conservative treatment. Abdominal ultrasound confirmed portal hypertension. Serial endoscopy on day 14, 17 and 1-month evaluation showed grade II-III esophageal varices and severe hypertensive portal gastropathy. Abdominal CT scan with contrast within 1 week after discharge revealed thrombus along ± 5.8 cm, splenomegaly with dilated splenic vein, dilatation and tourtosity of the left gastric vein and visualized distal esophageal vein. Liver biopsy 2 months after hospitalization showed hepatocytes with extensive hydropic degeneration with fibrosis (F3).

AB - Splenic Vein Thrombosis (SpVT) in a young patient with non-hepatitis B and C liver cirrhosis is an infrequent case generating hemorrhagic manifestations. Herein we report a 28-year-old man presenting with hematemesis, melena, and features of liver cirrhosis. Hematemesis, melena, and ascites resolve following a conservative treatment. Abdominal ultrasound confirmed portal hypertension. Serial endoscopy on day 14, 17 and 1-month evaluation showed grade II-III esophageal varices and severe hypertensive portal gastropathy. Abdominal CT scan with contrast within 1 week after discharge revealed thrombus along ± 5.8 cm, splenomegaly with dilated splenic vein, dilatation and tourtosity of the left gastric vein and visualized distal esophageal vein. Liver biopsy 2 months after hospitalization showed hepatocytes with extensive hydropic degeneration with fibrosis (F3).

KW - Liver biopsy

KW - Liver cirrhosis

KW - Portal hypertension

KW - Thrombosis

KW - Treatment

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U2 - 10.1016/j.amsu.2022.104439

DO - 10.1016/j.amsu.2022.104439

M3 - Article

AN - SCOPUS:85136576196

SN - 2049-0801

VL - 81

JO - Annals of Medicine and Surgery

JF - Annals of Medicine and Surgery

M1 - 104439

ER -

Splenic vein thrombosis in cirrhosis of the liver: A rare case

Abstract

Keywords

UN SDGs

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