Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities

Keyphrases

• Spleen Tyrosine Kinase 100%
• Stromal Cell Lines 100%
• Multilineage Differentiation 100%
• Human Mesenchymal Stem Cells (hMSCs) 100%
• Gamma Activity 100%
• Phospholipase Cγ 100%
• Osteogenic Differentiation 40%
• Adipogenic Differentiation 40%
• Cell Differentiation 30%
• Osteoblast 20%
• CCAAT/enhancer-binding Protein Homologous Protein 20%
• Adipocyte 20%
• Phospholipase C 20%
• Osteocalcin 10%
• Fatty Acid Binding Protein 4 (FABP4) 10%
• Lipid Droplets 10%
• Runt-related Transcription Factor 2 (Runx2) 10%
• Growth Hormone Receptor 10%
• Protein Expression 10%
• Receptor 2 10%
• Peroxisome Proliferator-activated Receptor 10%
• Kinase Phosphorylation 10%
• Fatty Acids 10%
• Distal-less Homeobox 5 10%
• Pharmacological Inhibitors 10%
• Signaling Pathway 10%
• Bone Metabolic Disorder 10%
• Adipogenesis 10%
• Linker Peptide 10%
• Expression Level 10%
• Matrix Mineralization 10%
• Osteogenesis 10%
• Mesenchymal Stromal Cells 10%
• Alkaline Phosphatase Activity 10%
• Multipotent Cells 10%
• Induced Signal 10%
• Small Interfering RNA (siRNA) 10%
• Gene Expression 10%
• Dual Role 10%
• Receptor-interacting Protein Kinase 1 (RIPK1) 10%
• Tyrosine Kinase Inhibition 10%
• B-cell Linker 10%

Biochemistry, Genetics and Molecular Biology

• Receptor Binding 10%