TY - JOUR
T1 - Some aspects of palladium-catalyzed cycloalkenylation
T2 - Developments of environmentally benign catalytic conditions and demonstration of tandem cycloalkenylation
AU - Toyota, Masahiro
AU - Rudyanto, Marcellino
AU - Ihara, Masataka
PY - 2002/5/17
Y1 - 2002/5/17
N2 - The influences of catalysts, substituent groups, and solvents on the palladium-catalyzed cycloalkenylation of cross-conjugated silyl enol ethers of 2-tert-butyldimethylsiloxy-5-(2-propenyl)-1,3-cyclohexadiene derivatives have been investigated. The catalytic reaction proceeded smoothly, even in aqueous media. The product ratios were influenced by the structure of substrates as well as solvents. In addition, it was found that the reaction is applicable to a tandem cyclization for the construction of cedrane skeleton.
AB - The influences of catalysts, substituent groups, and solvents on the palladium-catalyzed cycloalkenylation of cross-conjugated silyl enol ethers of 2-tert-butyldimethylsiloxy-5-(2-propenyl)-1,3-cyclohexadiene derivatives have been investigated. The catalytic reaction proceeded smoothly, even in aqueous media. The product ratios were influenced by the structure of substrates as well as solvents. In addition, it was found that the reaction is applicable to a tandem cyclization for the construction of cedrane skeleton.
UR - http://www.scopus.com/inward/record.url?scp=0037123673&partnerID=8YFLogxK
U2 - 10.1021/jo011169d
DO - 10.1021/jo011169d
M3 - Article
C2 - 12003549
AN - SCOPUS:0037123673
SN - 0022-3263
VL - 67
SP - 3374
EP - 3386
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 10
ER -