Sars-cov-2 antibody test for the hospitalised emergency obstetric cases: Useful or wasteful

M. P. Wardhana, Aditiawarman, Ernawati, N. C. Maniora, R. Aditya, K. E. Gumilar, B. Wicaksono, M. I.A. Akbar, A. Sulistyono, H. T. Juwono, Erry Gumilar Dachlan

Research output: Contribution to journalArticlepeer-review


Background: The emergency, labor and delivery conditions in obstetric cases need a clinical decision in a timely manner. The identification of Covid-19 especially in asymptomatic obstetric cases with ease and rapid antibody test need further investigation. Objective: To analyze the usability and performance of rapid antibody test in obstetric cases. Methods: Case control study using medical record on Covid-19 obstetric cases over 9 months with paired nasopharyngeal reverse transcriptase polymerase chain reaction severe acute respiratory syndrome coronavirus 2 and rapid antibody test results. Results: There were 92 Covid-19 obstetric cases (incidence: 17.4%) and 210 reactive rapid antibody test (seroprevalence: 39.6%). The sensitivity, specificity, positive predictive value and negative predictive value of rapid antibody tests was 89%, 24%, 40%, 80%. Symptomatic cases have lower sensitivity (73% vs. 96%) and higher specificity (48% vs. 20%). The presence of Covid-19 symptoms (p<0.05) and reactive rapid antibody test (p<0.001) were associated with Covid-19. Rapid antibody test will identify larger Covid-19 obstetric cases compare with the presence of symptom only (89.4% vs. 27.7%. Conclusion: Screening by rapid antibody test had a high sensitivity but low specificity. This test will identify more Covid-19 cases compared by symptoms only due to majority asymptomatic obstetric cases. This simple, cheap and rapid antibody test still has a place in initial screening to help identify Covid-19 in areas with widespread transmission and has limited capacity to carry out universal screening.

Original languageEnglish
Pages (from-to)56-63
Number of pages8
JournalNew Armenian Medical Journal
Issue number2
Publication statusPublished - 2021


  • Covid-19 infection
  • Perinatal
  • Pregnant


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