TY - CHAP
T1 - Role of Magnetic Nanomaterials in Biosafety and Bioregulation Facets
AU - Kusuma, Heri Septya
AU - Ukhurebor, Kingsley Eghonghon
AU - Aigbe, Uyiosa Osagie
AU - Onyancha, Robert Birundu
AU - Onyeachu, Ikenna Benedict
AU - Darmokoesoemo, Handoko
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
PY - 2023
Y1 - 2023
N2 - Due to their inherent magnetic properties and multifunctional design, magnetic nanoparticles (MNPs) fall within a category of highly customizable instruments that can be utilized as imaging agents, medicinal medications, biological devices, nano-electronic biosensors, or molecular nanotechnology for the delivery of drugs and genes. Human biosafety (HBS) of MNPs for clinical usage has grown to be a significant concern as the configuration, shape, chemical characteristics, and implant locations, along with their possible uses, become increasingly complex. Health hazards could also arise if MNPs build up in the cells or organs of humans or interact with their particles or chemical constituents. Consequently, this chapter reviews the special physical and chemical features, possible medical applications, as well as HBS in clinical studies of MNPs. Finally, the chapter will attempt to look at the challenges of practical translation and the prospective applications of MNPs in the biomedical fields. In conclusion, this chapter makes some recommendations for further study in nanomedicine.
AB - Due to their inherent magnetic properties and multifunctional design, magnetic nanoparticles (MNPs) fall within a category of highly customizable instruments that can be utilized as imaging agents, medicinal medications, biological devices, nano-electronic biosensors, or molecular nanotechnology for the delivery of drugs and genes. Human biosafety (HBS) of MNPs for clinical usage has grown to be a significant concern as the configuration, shape, chemical characteristics, and implant locations, along with their possible uses, become increasingly complex. Health hazards could also arise if MNPs build up in the cells or organs of humans or interact with their particles or chemical constituents. Consequently, this chapter reviews the special physical and chemical features, possible medical applications, as well as HBS in clinical studies of MNPs. Finally, the chapter will attempt to look at the challenges of practical translation and the prospective applications of MNPs in the biomedical fields. In conclusion, this chapter makes some recommendations for further study in nanomedicine.
KW - Biosafety
KW - Clinical trials
KW - Nanomedicine
KW - Nanoparticles
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=85169073190&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-36088-6_11
DO - 10.1007/978-3-031-36088-6_11
M3 - Chapter
AN - SCOPUS:85169073190
T3 - Engineering Materials
SP - 217
EP - 234
BT - Engineering Materials
PB - Springer Science and Business Media Deutschland GmbH
ER -
