Risk factors of emerging multidrug resistant Acinetobacter baumannii in burn patients at Burn Unit of Dr. Soetomo Hospital during January 2020 to December 2021

Medisa Primasari, Agus Santoso Budi, Lynda Hariani, Neneng Dwi Kurniati, Iswinarno Doso Saputro

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Burn injury patients are at high risk of infection as a result of the nature of the burn injury itself, including prolonged hospital stays, antibiotics use, treatment procedures, etc. In this era, nosocomial infections caused by Acinetobacter baumannii (A.ba) have increased significantly. This study was conducted to investigate the micro-organism pattern and the risk factors for burn patients with multi-drug resistant (MDR) Acinetobacter baumannii (A.ba) in the Burn Unit at Dr. Soetomo Hospital. Materials and Methods: We conducted a retrospective, observational study among burn patients with A.ba admitted to the Burn Unit at Dr. Soetomo Hospital from January 2020 to December 2021. Potential risk factors for MDR-A.ba were analysed by univariate and multivariate analysis. The patients diagnosed with MDR-A.ba wound infection were included in the case group. The patients diagnosed with non MDR, these are: (1) the patients isolated micro-organisms other than A.ba, (2) sterile isolates, and (3) the patients isolated as A.ba but not MDR, were included in the control group. Results: A total of 120 burn patients were included in this study. During this study, 24% burn patients were found to have Acinetobacter baumannii and 79% (from 24% of Acinetobacter baumannii) had MDR-A.ba. According to univariate analysis, risk factors that significant were: Abbreviated Burn Severity Index (ABSI) (p = 0,002; OR: 6.10; CI: 1,68-21,57); hospital Length Of Stay (LOS) (p < 0,000; OR: 6.95; CI: 2,56-18,91) and comorbid (p = 0,006; OR: 3,72; CI: 1,44-9,58). But, after analysed by multivariate analysis, only ABSI was the significant factor (p = 0,010; OR: 1,70; CI: 1,23-2,36). Conclusion: Based on univariate analysis, the significant risk factors for MDR-A.ba were: ABSI, hospital length of stay and comorbid. But after adjusted by multivariate analysis, only ABSI was the significant factor.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalMedical Journal of Malaysia
Volume79
Issue number2
Publication statusPublished - Mar 2024

Keywords

  • Acinetobacter baumannii
  • Burns
  • multidrug resistance

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