TY - JOUR
T1 - Relationship of benzene exposure to trans, trans-muconic acid and blood profile of shoe workers in romokalisari Surabaya, Indonesia
AU - Tualeka, Abdul Rohim
AU - Pathak, Yashwant
AU - Wibrata, Dwi Ananto
AU - Ilmi, Bahrul
AU - Ahsan, Ahsan
AU - Rahmawati, Pudji
AU - Russeng, Syamsiar S.
AU - Wahyu, Atjo
AU - Maspiyah, Maspiyah
AU - Sukarmin, Sukarmin
N1 - Publisher Copyright:
© 2019 Abdul Rohim Tualeka, Yashwant Pathak, Dwi Ananto Wibrata, Bahrul Ilmi, Ahsan Ahsan, Pudji Rahmawati, Syamsiar S. Russeng, Atjo Wahyu, Maspiyah Maspiyah, Sukarmin Sukarmin.
PY - 2019/3/15
Y1 - 2019/3/15
N2 - BACKGROUND: Benzene is a hazardous ingredient for health. Benzene is used as a latex glue solvent in the shoe industry. AIM: The purpose of the study was to analyse the relationship between benzene exposure with trans, trans-muconic acid (t, t-MA) and the blood profile of shoe workers in Romokalisari Surabaya. METHODS: The study was a cross-sectional design conducted in the shoe industry in Romokalisari Surabaya with some subjects of 20 shoe workers. Data collection was carried out by measuring benzene levels conducted at 8 measurement points in Surabaya Romokalisari, taking workers' blood, measuring body weight and conducting interviews with respondents. Data were analysed using correlation tests. RESULTS: The results showed that there was no relationship between benzene levels with t, t-MA (p-value = 0.205), there was no relationship between benzene Risk Quotient (RQ) and t, t-MA (p-value = 0.271) and there was no relationship between the Excess Cancer Risk (ECR) and blood profile of workers in Romokalisari. However, there were some abnormal blood profile parameters due to exposure to benzene although it was small. CONCLUSIONS: It seems another factors such as length of work, nutritional status, duration of exposure, weight, and frequency of exposure have a considerable contribution in the determination of intake of xenobiotic ingredients in the body to cause health effects especially blood profiles.
AB - BACKGROUND: Benzene is a hazardous ingredient for health. Benzene is used as a latex glue solvent in the shoe industry. AIM: The purpose of the study was to analyse the relationship between benzene exposure with trans, trans-muconic acid (t, t-MA) and the blood profile of shoe workers in Romokalisari Surabaya. METHODS: The study was a cross-sectional design conducted in the shoe industry in Romokalisari Surabaya with some subjects of 20 shoe workers. Data collection was carried out by measuring benzene levels conducted at 8 measurement points in Surabaya Romokalisari, taking workers' blood, measuring body weight and conducting interviews with respondents. Data were analysed using correlation tests. RESULTS: The results showed that there was no relationship between benzene levels with t, t-MA (p-value = 0.205), there was no relationship between benzene Risk Quotient (RQ) and t, t-MA (p-value = 0.271) and there was no relationship between the Excess Cancer Risk (ECR) and blood profile of workers in Romokalisari. However, there were some abnormal blood profile parameters due to exposure to benzene although it was small. CONCLUSIONS: It seems another factors such as length of work, nutritional status, duration of exposure, weight, and frequency of exposure have a considerable contribution in the determination of intake of xenobiotic ingredients in the body to cause health effects especially blood profiles.
KW - Benzene
KW - Blood Profile
KW - Shoe Worker, T
KW - T-MA
UR - http://www.scopus.com/inward/record.url?scp=85064128812&partnerID=8YFLogxK
U2 - 10.3889/oamjms.2019.136
DO - 10.3889/oamjms.2019.136
M3 - Article
AN - SCOPUS:85064128812
SN - 1857-5749
VL - 7
SP - 816
EP - 823
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
IS - 5
ER -