Regenerative medicine: From basic research to clinical application in physical medicine and rehabilitation

The present paper aims to report the aspect of physical medicine and rehabilitation in regenerative medicine. First, description the conceptual of rehabilitation. Secondly, briefly review the regenerative studies related with cases in the field of rehabilitation. Thirdly, suggestion for integrating regenerative therapy into rehabilitation strategies. The function status associated with physical activity is a health indicator and is the domain of quality of life. The effectiveness of rehabilitation interventions to restore physical functioning can be enhanced by the use of regenerative therapies. To investigate the potential of cellular therapy for the successful improvement of functional status, a paradigm shift of rehabilitation treatment and research is required. The vertical integration of rehabilitation and regeneration since the onset of therapeutic intervention allows the goal to be faster and more effective. The translation of stem cell therapy to a positive clinical change depends on the micro or niche environment for life control of stem cells, proliferation and regeneration. Rehabilitation strategies such as exercise and neuromuscular electrical stimulation (NMES) is required to optimize stem cell transplantation. Biosciences and human functioning research in rehabilitation as a core component of future rehabilitation strategies in regenerative therapies.