Properties of Tilapia Collagen as a Biomaterial for Tissue Engineering: A Review

Norhidayu Muhamad Zain, Syafiqah Saidin, Agung Sosiawan

Research output: Contribution to journalConference articlepeer-review

7 Citations (Scopus)


Collagen is one of the common biopolymers used as a biomaterial in tissue engineering applications due to its biocompatibility and biodegradability properties. Collagen derived from various sources and mostly found in porcine and bovine skin. However, due to religious concerns and the dangers of animal-borne diseases possesses by these mammalian derived collagens, marine collagens are extensively investigated as an alternative to substitute mammalian collagens in tissue engineering applications. Among those marine collagens, tilapia (Oreochromis niloticus) collagens are known to have a great potential to be used as biomaterials for tissue engineering application due to its higher thermal stability compared to other marine sources. Therefore, this study aims to review chemical and biological properties of tilapia collagen as a biomaterial for tissue engineering applications. The contents are mainly focused on the extraction yield, amino acid composition, thermal stability, cross-linking, biocompatibility, biodegradability, immunogenicity and hemostasis of tilapia collagen.

Original languageEnglish
Article number012021
JournalIOP Conference Series: Materials Science and Engineering
Issue number1
Publication statusPublished - 18 Dec 2020
Event1st International Conference on Science, Engineering and Technology, ICSET 2020 - Penang, Malaysia
Duration: 27 Feb 2020 → …


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