Progress on Applying Carbon Dots for Inhibition of RNA Virus Infection

Yaung Kwee, Yiqun Zhou, Mochamad Zakki Fahmi, Madhuri Sharon, Alfinda Novi Kristanti

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Viral infection is a globally leading health issue. Annually, new lethal RNA viruses unexpectedly emerged and mutated threatening health and safety. Meanwhile, it is urgent to explore novel antiviral agents, which, however, takes years to be clinically available. Nonetheless, the development of carbon dots (CDs) in the past 20 years has exhibited their vast application potentials and revealed their promising capacity as future antiviral agents considering their versatile properties and significant antiviral responses. Thus, CDs have been widely investigated as an alternative of traditional chemotherapy for inhibiting viral infection and replication in vitro. Meanwhile, attempts to apply CDs to in vivo systems are in high demand. In this review, recent developments of CDs-based antiviral therapies are systematically summarized. Furthermore, the role of CDs in photodynamic inactivation to kill viruses or bacteria is briefly discussed.

Original languageEnglish
Pages (from-to)436-450
Number of pages15
JournalNanotheranostics
Volume6
Issue number4
DOIs
Publication statusPublished - 2022

Keywords

  • RNA virus
  • antiviral therapy
  • carbon dots
  • nanomedicine
  • virus infection treatment

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