Abstract
This study aimed to determine the prevalence of multidrug-resistant (MDR) bacterial isolates in urinary tract infections (UTI) patients in Indonesia, where access to appropriate antibiotic treatment may be limited. A cross-sectional study was conducted from January 2020 to December 2022, with 308 bacterial isolates from UTIs cultured and tested for antimicrobial susceptibility. The most identified bacterial isolate was Escherichia coli (39.6 %), followed by Klebsiella pneumoniae (11.6 %) and Staphylococcus spp. (11.03 %). The overall prevalence of MDR bacterial isolates was 35 %, with the highest resistance observed to ampicillin (60 %) and cotrimoxazole (50 %). Independent risk factors for the development of MDR UTIs included age (p = 0.03) and male sex (p = 0.02). These findings underscore the need for ongoing monitoring of antibiotic resistance patterns and the development of antimicrobial stewardship programs to address this public health issue in Indonesia.
Original language | English |
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Article number | 100359 |
Journal | Clinical Infection in Practice |
Volume | 22 |
DOIs | |
Publication status | Published - Apr 2024 |
Keywords
- Antibiotic
- Health risk
- Indonesia
- Multi-drug resistance
- Urinary tract infections