Preparation and Characterization of Thin Film Sorbent Based on Self Assembly Polyelectrolyte Multilayers for Drugs Extractor

Eviomitta Rizki Amanda, Mohd Marsin Sanagi, Wan Aini Wan Ibrahim, Yanuardi Raharjo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

New materials based on self-assembled polyelectrolyte multilayers (PEM) thin film sorbents have been successfully developed. Several important coating parameters include the pH of the coating solution, the addition of salt to the coating solution, the dipping time, and the number of bilayers were optimized for drug extractors using the thin film micro extraction (TFME) technique. Optimum conditions were evaluated by the highest extraction performance for tricyclic antidepressant drugs (TCAs). Cellulose acetate membrane was chosen as the support material. Meanwhile, polyelectrolyte materials, namely poly (allyl amine hydrochloride) (PAAH) and poly(styrene sulfonic acid) (PSS) were chosen as coating materials. PAAH and PSS are deposited on the surface of the supporting material repeatedly. The results showed that the optimum coating conditions were pH PAAH 2 and PSS 2, no salt was added to the coating solution, the immersion time for each layer was 5 minutes, and the number of bilayers was 5. The optimized material was characterized by attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), field emission-scanning electron microscopy (FESEM), and thermogravimetric-differential thermal analyzer (TG-DTA). The addition of PEM to the CA membrane also increased the thermal stability of CA-PEM. The results are inspiring and indicate that this sorbent has a great potential for thin film extraction sorbent and also suitable for thermal desorption application.

Original languageEnglish
Title of host publication8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021
EditorsAnjar Tri Wibowo, M. Fariz Fadillah Mardianto, Riries Rulaningtyas, Satya Candra Wibawa Sakti, Muhammad Fauzul Imron, Rico Ramadhan
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735442610
DOIs
Publication statusPublished - 25 Jan 2022
Event8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021 - Surabaya, Indonesia
Duration: 25 Aug 202126 Aug 2021

Publication series

NameAIP Conference Proceedings
Volume2554
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021
Country/TerritoryIndonesia
CitySurabaya
Period25/08/2126/08/21

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