TY - JOUR
T1 - Potential of Bidara Leaf as Adjunctive Therapy against Breast Cancer Cell Line
T2 - A Review
AU - Yansen, Ifuling Audrein
AU - Budhy, Theresia Indah
AU - Nugraha, Alexander Patera
AU - Joestandari, Florentina
AU - Noor, Tengku Natasha Eleena Binti Tengku Ahmad
N1 - Publisher Copyright:
© RJPT All right reserved.
PY - 2023/11
Y1 - 2023/11
N2 - Background: Breast cancer or Carcinoma mammae is a malignancy that damage the gland ducts, and breast supporting tissues. Breast cancer is ranked first as a malignancy that often occurs in the world. The majority of women with breast cancer will have many surgeries. Chemotherapy is frequently used in conjunction with surgery. However, the side effects of chemotherapy drugs can damage healthy cells. Bidara leaf are one of the most promising sources of bioactive compounds for the pharmaceutical field in the treatment of breast cancer. Aims: This review article aims to describe the several types of Bidara leaf that contain compounds and anticancer activity that have potential as alternative treatments for breast cancer through narrative review. Review:This review article discusses several types of Bidara leaf and their anticancer activity. Conclusion: From the results of a journal review, it was found that several types of Bidara leaf with breast anticancer activity were Ziziphus spina christi, Zizyphus mauritiana, Ziziphus nummularia, with various activities such as cytotoxicity, antiproliferative, proapoptotic, and proinflammatory on the MCF-7 breast cancer cell line.
AB - Background: Breast cancer or Carcinoma mammae is a malignancy that damage the gland ducts, and breast supporting tissues. Breast cancer is ranked first as a malignancy that often occurs in the world. The majority of women with breast cancer will have many surgeries. Chemotherapy is frequently used in conjunction with surgery. However, the side effects of chemotherapy drugs can damage healthy cells. Bidara leaf are one of the most promising sources of bioactive compounds for the pharmaceutical field in the treatment of breast cancer. Aims: This review article aims to describe the several types of Bidara leaf that contain compounds and anticancer activity that have potential as alternative treatments for breast cancer through narrative review. Review:This review article discusses several types of Bidara leaf and their anticancer activity. Conclusion: From the results of a journal review, it was found that several types of Bidara leaf with breast anticancer activity were Ziziphus spina christi, Zizyphus mauritiana, Ziziphus nummularia, with various activities such as cytotoxicity, antiproliferative, proapoptotic, and proinflammatory on the MCF-7 breast cancer cell line.
KW - Bidara leaf
KW - Cancer
KW - Cytotoxic
KW - Medicine
KW - Non-communicable disease
UR - http://www.scopus.com/inward/record.url?scp=85181217160&partnerID=8YFLogxK
U2 - 10.52711/0974-360X.2023.00895
DO - 10.52711/0974-360X.2023.00895
M3 - Review article
AN - SCOPUS:85181217160
SN - 0974-3618
VL - 16
SP - 5532
EP - 5535
JO - Research Journal of Pharmacy and Technology
JF - Research Journal of Pharmacy and Technology
IS - 11
ER -