Potential and challenges for an integrated management of tuberculosis, diabetes mellitus, and hypertension: A scoping review protocol

Vitri Widyaningsih, Ratih Puspita Febrinasari, Victoria Sari, Clarissa Augustania, Bintang Verlita, Chatarina Wahyuni, Bachti Alisjahbana, Ailiana Santosa, Nawi Ng, Ari Probandari

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


In many low- and middle-income countries (LMICs), the epidemiological transition is characterized by an increased burden of non-communicable diseases (NCDs) and the persistent challenge of infectious diseases. The transmission of tuberculosis, one of the leading infectious diseases, can be halted through active screening of risk groups and early case findings. Studies have reported comorbidities between tuberculosis (TB) and NCDs, which necessitates the development of an integrated disease management model. This scoping review discusses the possibilities and problems of integration in managing TB and NCDs, with a particular emphasis on diabetic mellitus (DM) and hypertension screening and control. We will conduct this review following Arksey and O’Malley’s framework for scoping review. We will use key terms related to integrated management, i.e., screening, diagnosis, treatment, and care, of TB, DM, and hypertension in PubMed, Scopus Database, and ScienceDirect for research published from January 2005 to July 2021. This review will also consider grey literature, including unpublished literature and international disease management guidelines on TB, DM, and hypertension from WHO or other health professional organization. We will export the search results to citation manager software (EndNote). We will remove duplicates and apply the inclusion and exclusion criteria to identify the set of papers for the review. After screening the titles and abstract, two authors will independently review the full text of selected studies and extract the data. We will synthesize all selected studies qualitatively and the results will be discussed with the experts. The results will be used as the basis of the development of a guideline for integrated TB, DM, and hypertension management.

Original languageEnglish
Article numbere0271323
JournalPLoS ONE
Issue number7 July
Publication statusPublished - Jul 2022


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