Potency of okra fruit extract (Abelmoschus esculentus) against Porphyromonas Gingivalis as the cause of chronic periodontitis

Porphyromonas gingivalis (P. gingivalis) is an etiological agent of chronic periodontitis which is the main component of oral cavity microorganism. Porphyromonas gingivalis correlates with chronic periodontitis because it has the ability to avoid host immunity without inhibiting the inflammatory response that occurs which greatly benefits the presence of P. gingivalis and other bacteria while gingival crevicular fluid is an important source of nutrition because it contains peptides and iron. To prove that okra (Abelmoschus esculentus) fruit extract has the potential to inhibit and kill P. gingivalis which is a microorganism that causes chronic periodontitis. Minimal inhibitory concentration (MIC) and Minimal bactericidal concentration (MBC) were determined by using a serial dilution test. One Way Anova test showed a significant difference (p = 0.000) then based on the Tukey HSD test showed a significant difference between the okra fruit extract (100%, 3.125%, 1.565% concentration) group with positive control. Okra fruit extract have potency to eliminate in P.gingivalis that causes aggressive periodontitis indicated by MIC at concentrations 3.125% and MBC at concentrations of 6.25%.