Phytoconstituents of Genus Micromelum and Their Bioactivity—a Review

Tin Myo Thant, Nanik Siti Aminah, Alfinda Novi Kristanti, Rico Ramadhan, Hnin Thanda Aung, Yoshiaki Takaya

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)

Abstract

The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.

Original languageEnglish
JournalNatural Product Communications
Volume15
Issue number5
DOIs
Publication statusPublished - 2020

Keywords

  • Micromelum
  • Rutaceae
  • coumarins
  • flavonoids
  • quinolone and carbazole alkaloids

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