TY - JOUR
T1 - Phytoconstituents of Genus Micromelum and Their Bioactivity—a Review
AU - Thant, Tin Myo
AU - Aminah, Nanik Siti
AU - Kristanti, Alfinda Novi
AU - Ramadhan, Rico
AU - Aung, Hnin Thanda
AU - Takaya, Yoshiaki
N1 - Publisher Copyright:
© The Author(s) 2020.
PY - 2020
Y1 - 2020
N2 - The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.
AB - The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.
KW - Micromelum
KW - Rutaceae
KW - coumarins
KW - flavonoids
KW - quinolone and carbazole alkaloids
UR - http://www.scopus.com/inward/record.url?scp=85087965750&partnerID=8YFLogxK
U2 - 10.1177/1934578X20927124
DO - 10.1177/1934578X20927124
M3 - Review article
AN - SCOPUS:85087965750
SN - 1934-578X
VL - 15
JO - Natural Product Communications
JF - Natural Product Communications
IS - 5
ER -