Physical evaluation of PCL-AgNPs biocomposites as guided tissue regeneration membrane

Mohammad Bagus Lazuardi, Prihartini Widiyanti, Adri Supardi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Dental and mouth problems in Indonesia during 2007 to 2013 reportedly increased from 23.2% to 25.9% with the projection 65.275 million people with cases of periodontitis reaching 42.8%. One of clinical treatment of periodontitis is by using Guided Tissue Regeneration (GTR) method. This research was conducted to synthesize GTR membrane from Polycaprolactone (PCL) which is composed with AgNPs of Aloe vera biosynthesis product using electrospinning instrument. GTR membranes were synthesized by forming ratio of acetone and AgNPs which was obtained by mixing 30% Aloe vera extract with AgNO3 solution where AgNPs had been characterized previously using XRD and PSA. In this study the comparison of solvents done as 100/0 (control), 90/10, 80/20, and 70/30 (v/v). Obtained GTR membranes are characterized by Scanning Electron Microscope and tensile strength characterization. From the analysis results known the best composition of PCL-AgNPs biocomposite as GTR membrane was found on the variable with ratio 70/30 (v/v) with fiber size 111,6 ± 22 nm, UTS value equal to 4,37 MPa with elongation equal to 204%. Based on the results of characterization, it showed that biocomposites PCL-AgNPs Aloe vera biosynthesis products have good potential as a guided tissue regeneration membrane.

Original languageEnglish
Pages (from-to)155-161
Number of pages7
JournalJurnal Teknologi (Sciences and Engineering)
Issue number1
Publication statusPublished - 2020


  • AgNPs
  • Electrospinning
  • Guided tissue regeneration
  • Polycaprolactone


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