Phylogenetic and pathotypic characterization of avian paramyxovirus serotype 1 (APMV-1) in Indonesia

Arif Nur Muhammad Ansori, Viol Dhea Kharisma, Alexander Patera Nugraha

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Newcastle disease (ND) is recognized as one of the highly contagious and lethal infectious diseases of poultry industry globally. ND is caused by avian paramyxovirus type-1 (APMV-1) or Newcastle disease virus (Paramyxoviridae: Avulavirus). ND outbreaks have occurred in many parts of the world including Indonesia, it brought an implication on a large economic loss due to the mortality and a trade embargo on poultry in the outbreak area. This study was to characterize 58 isolates of Newcastle disease virus (NDV) collected from GenBank® (National Center for Biotechnology Information, USA) from 1976 to 2020. Interestingly, we revealed the data of pathotype and phylogenetic analysis of the circulating NDV isolated from Indonesia based on the fusion protein gene. In sum, the results from the current study suggested that the data of pathotype and phylogenetic analysis can be used as a reference for vaccine design in Indonesia.

Original languageEnglish
Pages (from-to)3023-3027
Number of pages5
JournalBiochemical and Cellular Archives
Volume20
DOIs
Publication statusPublished - 2020

Keywords

  • Avian paramyxovirus type-1
  • Bioinformatics analysis
  • Communicable disease
  • Newcastle disease
  • Vaccine

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