Abstract
The aim of this study was to determine the effect of sukun leaf (Artocarpus altilis) extract on collagen density of excision wound healing in albino rats (Rattus norvegicus). A total of 20 male albino rats were randomly devided into five groups, there were negative control (K-) treated with ointment base, positive control (K+) treated with povidone iodine 10%, treated groups (P1, P2, P3) treated with sukun leaf extract ointment 6,25%; 12,5%; and 25%. Treatment was given every other day for fourteen days. Results of the nonparametric test Kruskal-Wallis showed significant difference (p<0,05) and continued with the Mann-Whitney test. Collagen density groups of P1, P2, and P3 did not different significantly (p>0,05), but significantly different from group K-and K+. The conclusion of this study was sukun leaf extract effective to increase the density of collagen in the healing process of excision wound.
Translated title of the contribution | The Effect of Sukun Leaf (Artocarpus altilis) Extract on Collagen Density of Excision Wound Healing in Albino Rats (Rattus norvegicus) |
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Original language | Indonesian |
Pages (from-to) | 25-30 |
Number of pages | 6 |
Journal | Jurnal Medik Veteriner |
Volume | 3 |
Issue number | 1 |
DOIs | |
Publication status | Published - Apr 2020 |
Keywords
- collagen
- excision
- sukun leaf
- wound healing