TY - JOUR
T1 - Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
AU - Hariyadi, Dewi Melani
AU - Isnaeni, Isnaeni
AU - Sudarma, Sisunandar
AU - Suciati, Suciati
AU - Rosita, Noorma
N1 - Publisher Copyright:
© 2020 Journal of Advanced Pharmaceutical Technology & Research | Published by Wolters Kluwer-Medknow.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Cocos nucifera Linn., which contain lauric acid has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the C. nucifera L. Extract from Kopyor coconut. Extract were tested for antibacterial against P. acnes ATCC 11827. In this research, C. nucifera L. extract of 1 and 5% were formulated as an active agent of peel off antiacne emulgel mask-containing carbomer 940 in various concentration (1% and 1.5%). The peel-off emulgel mask of C. nucifera L extract was then evaluated in terms of viscosity, pH, drying time, spreadability, and antibacterial activity. The selected formula was formula containing 5% of extract and 1% of carbomer 940. This formula had pH that suitable with skin pH 4.5-6.5, had good spreadability, and also produced highest antibacterial activity against P. acnes.
AB - Cocos nucifera Linn., which contain lauric acid has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the C. nucifera L. Extract from Kopyor coconut. Extract were tested for antibacterial against P. acnes ATCC 11827. In this research, C. nucifera L. extract of 1 and 5% were formulated as an active agent of peel off antiacne emulgel mask-containing carbomer 940 in various concentration (1% and 1.5%). The peel-off emulgel mask of C. nucifera L extract was then evaluated in terms of viscosity, pH, drying time, spreadability, and antibacterial activity. The selected formula was formula containing 5% of extract and 1% of carbomer 940. This formula had pH that suitable with skin pH 4.5-6.5, had good spreadability, and also produced highest antibacterial activity against P. acnes.
KW - Antibacterial activity
KW - Cocos nucifera L. extract
KW - Propionibacterium acnes
KW - carbomer 940
UR - http://www.scopus.com/inward/record.url?scp=85094592137&partnerID=8YFLogxK
U2 - 10.4103/japtr.JAPTR_51_20
DO - 10.4103/japtr.JAPTR_51_20
M3 - Article
AN - SCOPUS:85094592137
SN - 2231-4040
VL - 11
SP - 220
EP - 225
JO - Journal of Advanced Pharmaceutical Technology and Research
JF - Journal of Advanced Pharmaceutical Technology and Research
IS - 4
ER -