Paliasa (Kleinhovia hospita L.) As An Immunomodulator: A Scooping Review

Paliasa (Kleinhovia hospita L.) is one of the tropical plants of South Sulawesi that has high antioxidants with phenol compounds, alkaloids, flavonoids, polyphenols, kaempferol, quercetin, and cyanogenic. Empirically, the Paliasa plant (Kleinhovia hospital L.) has been used to treat various diseases, such as cancer, stroke, hypertension, hepatitis, cirrhosis of the liver, diabetes mellitus, and allergies. The goal of the study was to see how effective Paliasa was as an immunomodulator. The literature review approach used is an online search using google chrome programs on PubMed and Google scholar sites with the keywords “Kleinhovia hospita L.”, immune system “,” immunomodulator “, and “inflammation”. The sources selected are national and international journals, which are then selected based on inclusion criteria, namely journals published between 2016 and 2021 as many as 20 journals with the type of research articles or original articles. While the exclusion criteria is a journal with a type of review article. The study found the anti-inflammatory and immunomodulatory activity of Paliasa. The benefit of research is to provide information about the efficacy of Paliasa as an immunomodulator to boost immunity.