Oral care colostrum effect on preterm infants fecal immunoglobulin a secretory level

Objective To evaluate whether oral care colostrum can increase fecal secretory immunoglobulin A levels in preterm infants. Methods Thirty-eight infants who met the inclusion criteria were randomized. Twenty colostrum oral care infants and eighteen control control infants. Colostrum oral care by giving as much as 0.1 ml of colostrum on each buccal mucosa for approximately 2 minutes on one side. The procedure is repeated every 4 hours for 3 days. Fecal secretory immunoglobulin A levels are taken from the first faecal after birth and 72 hours after colostrum administration. Fecal retrieval must first install a urine device so that the urine does not wet the sample. Result Fecal secretory immunoglobulin A level before treatment in the treatment group were 0.0633 ± 0.0037 mg/g feces higher than the control group 0.0166 ± 0.0139 mg/g feces, statistically there were no significant differences (p = 0.595). Fecal secretory immunoglobulin A level after treatment in the treatment group amounted to 1,1007 ± 0.2458 mg/g feces higher than the control group 0.6045 ± 0.2358 mg/g faeces, statistically there were no significant differences (p = 0.09). Difference in increase in secretory fecal immunoglobulin A levels after and before treatment in the treatment group 1.0374 ± 0.2575 mg/g feces is higher than the control group 0.5879 ± 0.2385 mg/g feces, statistically there were no significant differences (p = 0.09). Conclusion Oral care colostrum has been shown to increase secretory immunoglobulin A levels in preterm infants before colostrum oral care, and colostrum oral care has the potential to increase faecal secretory immunoglobulin A level than controls in preterm infants.