TY - JOUR
T1 - Ochratoxin A in coffee and coffee-based products
T2 - A global systematic review, meta-analysis, and probabilistic risk assessment
AU - Fakhri, Yadolah
AU - Mahdavi, Vahideh
AU - Ranaei, Vahid
AU - Pilevar, Zahra
AU - Sarafraz, Mansour
AU - Mahmudiono, Trias
AU - Khaneghah, Amin Mousavi
N1 - Publisher Copyright:
© 2022 Walter de Gruyter GmbH, Berlin/Boston 2022.
PY - 2022
Y1 - 2022
N2 - Contamination of food with mycotoxins can pose harmful effects on the health of consumers in the long term. Coffee contamination with mycotoxins has become a global concern. This study attempted to meta-analyze the concentration and prevalence of ochratoxin A (OTA) in coffee products and estimate consumers' health risks. The search was conducted among international databases, including Scopus, PubMed, Embase, and Web of Science, for 1 January 2010 to 1 May 2022. The concentration and prevalence of OTA in coffee products were meta-analyzed according to country subgroups. Health risk assessment was conducted based on Margin of Exposures (MOEs) using the Monte Carlo simulation (MCS) technique. The three countries that had the highest Pooled concentration of OTA in coffee were observed in Chile (100.00%), Kuwait (100.00%), and France (100.00%). The overall prevalence of OTA in coffee products was 58.01%, 95% CI (48.37-67.39). The three countries that had the highest concentration of OTA were Philippines (39.55 μg/kg) > Turkey (39.32 μg/kg) > and Panama (21.33 μg/kg). The mean of MOEs in the adult consumers in Panama (9,526) and the Philippines (8,873) was lower than 10,000, while the mean of MOEs in other countries was higher than 10,000. Therefore, monitoring and control plans should be carried out in different countries.
AB - Contamination of food with mycotoxins can pose harmful effects on the health of consumers in the long term. Coffee contamination with mycotoxins has become a global concern. This study attempted to meta-analyze the concentration and prevalence of ochratoxin A (OTA) in coffee products and estimate consumers' health risks. The search was conducted among international databases, including Scopus, PubMed, Embase, and Web of Science, for 1 January 2010 to 1 May 2022. The concentration and prevalence of OTA in coffee products were meta-analyzed according to country subgroups. Health risk assessment was conducted based on Margin of Exposures (MOEs) using the Monte Carlo simulation (MCS) technique. The three countries that had the highest Pooled concentration of OTA in coffee were observed in Chile (100.00%), Kuwait (100.00%), and France (100.00%). The overall prevalence of OTA in coffee products was 58.01%, 95% CI (48.37-67.39). The three countries that had the highest concentration of OTA were Philippines (39.55 μg/kg) > Turkey (39.32 μg/kg) > and Panama (21.33 μg/kg). The mean of MOEs in the adult consumers in Panama (9,526) and the Philippines (8,873) was lower than 10,000, while the mean of MOEs in other countries was higher than 10,000. Therefore, monitoring and control plans should be carried out in different countries.
KW - Ochratoxin A
KW - coffee products
KW - meta-analysis
KW - risk assessment
UR - http://www.scopus.com/inward/record.url?scp=85142770299&partnerID=8YFLogxK
U2 - 10.1515/reveh-2022-0115
DO - 10.1515/reveh-2022-0115
M3 - Review article
AN - SCOPUS:85142770299
SN - 0048-7554
JO - Reviews on Environmental Health
JF - Reviews on Environmental Health
ER -
