New Quantum Approach on Epilepsy Drug 3'-Aminothymidin Based on Pharmacokinetic, Topological and Molecular Docking Report

Herri Trilaksana, Thanmayalaxmi Darbhe, Athisaya Raja Suvitha, Rajesh Gangatharan, Anjali Nayak, Paramita Das

Research output: Contribution to journalArticlepeer-review

Abstract

In recent years, agricultural development has been one of the most significant initiatives. When introducing a product, it is essential to take into account clinical testing using ADMET qualities, pharmacokinetic properties, topological area, mass spectral analysis, and a report on microspecies dispersion. The creation of in silico models has been hampered by the desire of bio researchers. Pharmacokinetic properties control the amount of agricultural products consumed and how the body handles drugs. The current DFT research will help the biological industry adopt a new strategy for drug development. We investigated various aspects of the drug azidothymidine (AZDM). A variety of useful azidothymidine production values were discovered after further research into the docking results against two protein targets of the SNX2 gene for their antiepileptic activity.

Original languageEnglish
Article number432
JournalBiointerface Research in Applied Chemistry
Volume13
Issue number5
DOIs
Publication statusPublished - 15 Oct 2023

Keywords

  • ADMET
  • AZDM
  • Health care drug development
  • pharmacokinetic properties
  • topological polar surface area

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