TY - JOUR
T1 - Neuroprotective activity of Indonesian traditional herbal medicine
T2 - A systematic review
AU - Agil, Mangestuti
AU - Kusumawati, Idha
AU - Muslikh, Faisal Akhmal
AU - Ma’arif, Burhan
N1 - Publisher Copyright:
© 2023 Mangestuti Agil et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
PY - 2023
Y1 - 2023
N2 - The brain requires good care for it regulates all systems and functions of the human body’s organs. Good care can also prevent brain damage caused by the aging process and neurodegenerative diseases. Consuming herbs is one of the treatments for the brain. This study aims to provide an overview of the neuroprotective use of herbs in traditional Indonesian medicine. The method employed is a review of articles based on predetermined criteria. The plants were then reselected based on the plants used for the central nervous system (CNS) in the Cabe Puyang Manuscript. Cabe Puyang is a manuscript that describes the health benefits of various medicinal herbs. According to the criteria, 31 herbs acting as neuroprotective agents in Indonesia were discovered. The herbs were reselected based on the herbs used in the Cabe Puyang Manuscript for the CNS. Twelve herbs have been included in Indonesia’s traditional medicine system for use as neuroprotectors. These herbs are Zingiber officinale, Centella asiatica, Allium sativum, Andrographis paniculata, Piper nigrum, Coriandrum sativum, Piper retrofractum, Moringa oleifera, Ocimum sanctum, Kaempferia galangal, Ruta graveolens, and Acorus calamus. The Cabe Puyang Manuscript mentioned all of the selected herbs used as neuroprotectors in the Indonesian system of medicine. They all demonstrated a strong antioxidative and anti-inflammatory action in brain tissues. Both actions are manifestations of neurodegenerative pathologies.
AB - The brain requires good care for it regulates all systems and functions of the human body’s organs. Good care can also prevent brain damage caused by the aging process and neurodegenerative diseases. Consuming herbs is one of the treatments for the brain. This study aims to provide an overview of the neuroprotective use of herbs in traditional Indonesian medicine. The method employed is a review of articles based on predetermined criteria. The plants were then reselected based on the plants used for the central nervous system (CNS) in the Cabe Puyang Manuscript. Cabe Puyang is a manuscript that describes the health benefits of various medicinal herbs. According to the criteria, 31 herbs acting as neuroprotective agents in Indonesia were discovered. The herbs were reselected based on the herbs used in the Cabe Puyang Manuscript for the CNS. Twelve herbs have been included in Indonesia’s traditional medicine system for use as neuroprotectors. These herbs are Zingiber officinale, Centella asiatica, Allium sativum, Andrographis paniculata, Piper nigrum, Coriandrum sativum, Piper retrofractum, Moringa oleifera, Ocimum sanctum, Kaempferia galangal, Ruta graveolens, and Acorus calamus. The Cabe Puyang Manuscript mentioned all of the selected herbs used as neuroprotectors in the Indonesian system of medicine. They all demonstrated a strong antioxidative and anti-inflammatory action in brain tissues. Both actions are manifestations of neurodegenerative pathologies.
KW - Alternative medicine
KW - Cabe Puyang
KW - ancient manuscript
KW - herbs
KW - neuroprotector
UR - http://www.scopus.com/inward/record.url?scp=85179974530&partnerID=8YFLogxK
U2 - 10.7324/JAPS.2023.93645
DO - 10.7324/JAPS.2023.93645
M3 - Review article
AN - SCOPUS:85179974530
SN - 2231-3354
VL - 13
SP - 14
EP - 30
JO - Journal of Applied Pharmaceutical Science
JF - Journal of Applied Pharmaceutical Science
IS - 10
ER -