Neurological manifestations of hypokalemia: a case report

Vania Ayu Puspamaniar, Azizah Amimathul Firdha, Nurul Azizah, Hanik Badriyah Hidayati

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Hypokalemic Periodic Paralysis (HPP) is a neurological manifestation of hypokalemia, with a prevalence of 1 in 100,000. HPP is recognized by the sudden onset of muscle paralysis and low serum potassium. Due to its various causes, it may be misdiagnosed and neglected. We present a case of 42-year-old Asian female with weakness of both legs and cramps. The weakness was felt upon awakening from sleep. She also complained of palpitation, tiredness, sweating, heat intolerance, and hand tremors. In the recent weeks, her appetite increased. Periodic paralysis (PP) is characterized by bursts of painless muscle weakening. A possible cause of periodic paralysis is hypokalemia which was found in our case. Hyperthyroid is classified into potassium depletion by extra renal route which was found in this case. Management When managing a patient with sudden onset weakness or paralysis, it is crucial to consider the possibility of periodic paralysis. HPP is a rare but serious medical emergency. This should be suspected in any patient presenting with sudden muscle weakness. Prompt correction of any abnormalities in potassium levels can lead to rapid and complete symptom resolution. To avoid persistent or recurrent paralysis, any underlying causes should be effectively managed wherever possible.

Original languageEnglish
Pages (from-to)187-190
Number of pages4
JournalAnaesthesia, Pain and Intensive Care
Issue number1
Publication statusPublished - 1 Feb 2024


  • Hyperthyroid
  • Hypokalemia
  • Hypokalemic Periodic Paralysis
  • Paralysis


Dive into the research topics of 'Neurological manifestations of hypokalemia: a case report'. Together they form a unique fingerprint.

Cite this